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IHT has also been shown to suppress the cytotoxic signaling cascades activated by excess glutamate induced by ethanol withdrawal in the rat, preventing p30 activation and down-stream increase of presenilin 1 (PS1), A140 and A142 content in the prefrontal cortex of rats (Ryou et al., 2017)

This approach will help identify practices that not only minimize the carbon footprint but also reduce the overall environmental burden associated with animal production, ultimately contributing to global sustainability efforts [119]